The Boston Red Sox (22-22) and Detroit Tigers (28-15) wrap up their 3-game series Wednesday. First pitch from Comerica Park in Detroit is set for 6:40 p.m. ET. Let's analyze BetMGM Sportsbook's MLB odds around the Red Sox vs. Tigers odds and make our expert MLB picks and predictions for the best bets.

Detroit dominated Game 1 of this series yesterday with a 14-2 victory. The Tigers had 18 hits to the Red Sox's six with each team hitting two homers. Detroit is 6-2 in the last eight games, but 1-2 over the past three. Boston is 4-2 in the previous six games and 4-5 over the last nine.

Right-hander Bryse Wilson takes the mound as the White Sox look for their first sweep of the season. Here's the game day preview.

Life is good for the Detroit Tigers right now. A second straight dramatic walk-off win over the Boston Red Sox on Wednesday night has A.J. Hinch's team at an ML

Throughout this spring, the Red Sox have struggled to come back. Entering Tuesday night’s contest in Detroit, they were 7-15 when opponents scored first, 3-4 when tied after eight innings, 1-15

As the Red Sox face Tigers ace Tarik Skubal on Wednesday, they'll welcome back one of their top lefty mashers, who hasn't played since May 1.

Tarik Skubal set the stage for the Tigers to beat the Red Sox on Wednesday, climbing to 61 strikeouts with just two walks in his last seven starts.